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KLHL3 抗体 (AA 10-59)

The 兔 多克隆 anti-KLHL3 antibody is suitable to detect KLHL3 in samples from 人, 小鼠 和 大鼠. It has been validated for WB, ELISA, IHC 和 IF.
产品编号 ABIN1534174
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for KLHL3 抗体 (AA 10-59) (ABIN1534174)

抗原

See all KLHL3 抗体
KLHL3 (Kelch-Like 3 (KLHL3))

适用

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人, 小鼠, 大鼠

宿主

  • 52
  • 2
兔

克隆类型

  • 54
多克隆

标记

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  • 4
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This KLHL3 antibody is un-conjugated

应用范围

  • 42
  • 15
  • 13
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  • 9
  • 4
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  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

    • 15
    • 7
    • 7
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    AA 10-59

    原理

    KLHL3 Antibody

    特异性

    KLHL3 Polyclonal Antibody detects endogenous levels of KLHL3 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human KLHL3. AA range:10-59

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    KLHL3 (Kelch-Like 3 (KLHL3))

    别名

    KLHL3

    背景

    Synonyms: KLHL3, KIAA1129, Kelch-like protein 3

    Background: This gene is ubiquitously expressed and encodes a full-length protein which has an N-terminal BTB domain followed by a BACK domain and six kelch-like repeats in the C-terminus. These kelch-like repeats promote substrate ubiquitination of bound proteins via interaction of the BTB domain with the CUL3 (cullin 3) component of a cullin-RING E3 ubiquitin ligase (CRL) complex. Muatations in this gene cause pseudohypoaldosteronism type IID (PHA2D), a rare Mendelian syndrome featuring hypertension, hyperkalaemia and metabolic acidosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Mar 2012],

    Gene Name: KLHL3

    Protein Name: Kelch-like protein 3

    分子量

    64 kDa

    基因ID

    26249

    OMIM

    605775

    UniProt

    Q9UH77
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