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ZBTB33 抗体

The 兔 多克隆 anti-ZBTB33 antibody (ABIN7256410) specifically detects ZBTB33 in WB. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN7256410
发货至: 中国
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Quick Overview for ZBTB33 抗体 (ABIN7256410)

抗原

See all ZBTB33 抗体
ZBTB33 (Zinc Finger and BTB Domain Containing 33 (ZBTB33))

适用

  • 27
  • 11
  • 8
  • 8
  • 5
  • 5
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
人, 小鼠

宿主

  • 24
  • 4

克隆类型

  • 20
  • 8
多克隆

标记

  • 24
  • 2
  • 1
  • 1
This ZBTB33 antibody is un-conjugated

应用范围

  • 20
  • 13
  • 7
  • 5
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein of human ZBTB33 (NP_006768.1).

    亚型

    IgG
  • 应用备注

    WB 1:1000-1:3000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    ZBTB33 (Zinc Finger and BTB Domain Containing 33 (ZBTB33))

    别名

    ZBTB33

    背景

    This gene encodes a transcriptional regulator with bimodal DNA-binding specificity, which binds to methylated CGCG and also to the non-methylated consensus KAISO-binding site TCCTGCNA. The protein contains an N-terminal POZ/BTB domain and 3 C-terminal zinc finger motifs. It recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters. It may contribute to the repression of target genes of the Wnt signaling pathway, and may also activate transcription of a subset of target genes by the recruitment of catenin delta-2 (CTNND2). Its interaction with catenin delta-1 (CTNND1) inhibits binding to both methylated and non-methylated DNA. It also interacts directly with the nuclear import receptor Importin-alpha2 (also known as karyopherin alpha2 or RAG cohort 1), which may mediate nuclear import of this protein. Alternatively spliced transcript variants encoding the same protein have been identified.

    分子量

    Observed_MW: 74 kDa

    Calculated_MW: 74 kDa

    基因ID

    10009

    UniProt

    Q86T24
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