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VEGF 抗体

This anti-VEGF antibody is a 兔 多克隆 antibody detecting VEGF in IF. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7256020
发货至: 中国

Quick Overview for VEGF 抗体 (ABIN7256020)

抗原

See all VEGF 抗体
VEGF (Vascular Endothelial Growth Factor (VEGF))

适用

  • 82
  • 31
  • 20
  • 5
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 43
  • 39
  • 14
  • 2
  • 2
  • 1

克隆类型

  • 51
  • 47
  • 1
多克隆

标记

  • 44
  • 16
  • 6
  • 5
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This VEGF antibody is un-conjugated

应用范围

  • 76
  • 58
  • 41
  • 24
  • 20
  • 15
  • 11
  • 7
  • 6
  • 5
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Immunofluorescence (IF)
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein of human VEGF (NP_001165099.1).

    亚型

    IgG
  • 应用备注

    IF 1:50-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    VEGF (Vascular Endothelial Growth Factor (VEGF))

    别名

    VEGF

    背景

    This gene is a member of the PDGF/VEGF growth factor family. It encodes a heparin-binding protein, which exists as a disulfide-linked homodimer. This growth factor induces proliferation and migration of vascular endothelial cells, and is essential for both physiological and pathological angiogenesis. Disruption of this gene in mice resulted in abnormal embryonic blood vessel formation. This gene is upregulated in many known tumors and its expression is correlated with tumor stage and progression. Elevated levels of this protein are found in patients with POEMS syndrome, also known as Crow-Fukase syndrome. Allelic variants of this gene have been associated with microvascular complications of diabetes 1 (MVCD1) and atherosclerosis. Alternatively spliced transcript variants encoding different isoforms have been described. There is also evidence for alternative translation initiation from upstream non-AUG (CUG) codons resulting in additional isoforms. A recent study showed that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is antiangiogenic. Expression of some isoforms derived from the AUG start codon is regulated by a small upstream open reading frame, which is located within an internal ribosome entry site.

    基因ID

    7422

    UniProt

    P15692
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