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Cathepsin B 抗体

This anti-Cathepsin B antibody is a 兔 多克隆 antibody detecting Cathepsin B in IHC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7255051
发货至: 中国

Quick Overview for Cathepsin B 抗体 (ABIN7255051)

抗原

See all Cathepsin B (CTSB) 抗体
Cathepsin B (CTSB)

适用

  • 72
  • 27
  • 27
  • 7
  • 1
人, 小鼠, 大鼠

宿主

  • 55
  • 26
  • 3
  • 1
  • 1

克隆类型

  • 56
  • 30
多克隆

标记

  • 48
  • 5
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Cathepsin B antibody is un-conjugated

应用范围

  • 66
  • 41
  • 24
  • 23
  • 23
  • 18
  • 13
  • 13
  • 10
  • 5
  • 3
  • 3
Immunohistochemistry (IHC)
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein of human CTSB (NP_001899.1).

    亚型

    IgG
  • 应用备注

    IHC 1:50-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    Cathepsin B (CTSB)

    别名

    CTSB

    背景

    This gene encodes a member of the C1 family of peptidases. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate multiple protein products. These products include the cathepsin B light and heavy chains, which can dimerize to form the double chain form of the enzyme. This enzyme is a lysosomal cysteine protease with both endopeptidase and exopeptidase activity that may play a role in protein turnover. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer's disease, the most common cause of dementia. Overexpression of the encoded protein has been associated with esophageal adenocarcinoma and other tumors. Multiple pseudogenes of this gene have been identified.

    基因ID

    1508

    UniProt

    P07858

    途径

    Activation of Innate immune Response, Toll-Like Receptors Cascades
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