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Perforin 1 抗体

This anti-Perforin 1 antibody is a 兔 多克隆 antibody detecting Perforin 1 in WB, IHC 和 IF. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7254750
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Perforin 1 抗体 (ABIN7254750)

抗原

See all Perforin 1 (PRF1) 抗体
Perforin 1 (PRF1) (Perforin 1 (Pore Forming Protein) (PRF1))

适用

  • 103
  • 29
  • 8
  • 6
  • 5
  • 5
  • 2
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 65
  • 55
  • 8

克隆类型

  • 72
  • 56
多克隆

标记

  • 60
  • 14
  • 14
  • 6
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Perforin 1 antibody is un-conjugated

应用范围

  • 47
  • 44
  • 39
  • 23
  • 16
  • 11
  • 10
  • 7
  • 6
  • 5
  • 5
  • 4
  • 4
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein of human Perforin (NP_001076585.1).

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    Perforin 1 (PRF1) (Perforin 1 (Pore Forming Protein) (PRF1))

    别名

    Perforin

    背景

    The protein encoded by this gene has structural and functional similarities to complement component 9 (C9). Like C9, this protein creates transmembrane tubules and is capable of lysing non-specifically a variety of target cells. This protein is one of the main cytolytic proteins of cytolytic granules, and it is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis. Defects in this gene cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare and lethal autosomal recessive disorder of early childhood. Alternative splicing results in multiple transcript variants encoding the same protein.

    分子量

    Observed_MW: 70 kDa

    Calculated_MW: 61 kDa

    基因ID

    5551

    UniProt

    P14222

    途径

    Apoptosis, Caspase Cascade in Apoptosis
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