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Neurofibromin 1 抗体

The 兔 多克隆 anti-Neurofibromin 1 antibody is suitable to detect Neurofibromin 1 in samples from 人, 小鼠 和 大鼠. It has been validated for ELISA 和 IHC.
产品编号 ABIN7254607
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Neurofibromin 1 抗体 (ABIN7254607)

抗原

See all Neurofibromin 1 (NF1) 抗体
Neurofibromin 1 (NF1)

适用

  • 68
  • 54
  • 36
  • 2
  • 2
  • 2
  • 2
  • 1
人, 小鼠, 大鼠

宿主

  • 76
  • 8

克隆类型

  • 74
  • 10
多克隆

标记

  • 32
  • 5
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Neurofibromin 1 antibody is un-conjugated

应用范围

  • 39
  • 39
  • 28
  • 24
  • 15
  • 13
  • 10
  • 9
  • 9
  • 5
  • 5
  • 1
ELISA, Immunohistochemistry (IHC)
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Antigen affinity purification

    免疫原

    Synthetic peptide of human NF1

    亚型

    IgG
  • 应用备注

    IHC 1:40-1:250, ELISA 1:500-1000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.7 mg/mL

    缓冲液

    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    Neurofibromin 1 (NF1)

    别名

    NF1

    背景

    This gene product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene.NF1 (Neurofibromin 1) is a Protein Coding gene. Diseases associated with NF1 include Neurofibromatosis-Noonan Syndrome and Neurofibromatosis, Type 1. Among its related pathways are Development VEGF signaling via VEGFR2 - generic cascades and RET signaling. GO annotations related to this gene include binding and phosphatidylcholine binding.

    UniProt

    P21359

    途径

    cAMP Metabolic Process, Regulation of long-term Neuronal Synaptic Plasticity
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