Neurofibromin 1 抗体
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- 抗原 See all Neurofibromin 1 (NF1) 抗体
- Neurofibromin 1 (NF1)
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Neurofibromin 1 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC)
- 产品特性
- Polyclonal Antibody
- 纯化方法
- Antigen affinity purification
- 免疫原
- Synthetic peptide of human NF1
- 亚型
- IgG
- Top Product
- Discover our top product NF1 Primary Antibody
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- 应用备注
- IHC 1:40-1:250, ELISA 1:500-1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1.7 mg/mL
- 缓冲液
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- Neurofibromin 1 (NF1)
- 别名
- NF1 (NF1 产品)
- 背景
- This gene product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene.NF1 (Neurofibromin 1) is a Protein Coding gene. Diseases associated with NF1 include Neurofibromatosis-Noonan Syndrome and Neurofibromatosis, Type 1. Among its related pathways are Development VEGF signaling via VEGFR2 - generic cascades and RET signaling. GO annotations related to this gene include binding and phosphatidylcholine binding.
- UniProt
- P21359
- 途径
- cAMP Metabolic Process, Regulation of long-term Neuronal Synaptic Plasticity
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