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NOTCH4 抗体

This anti-NOTCH4 antibody is a 兔 多克隆 antibody detecting NOTCH4 in WB, ELISA 和 IHC. Suitable for 人.
产品编号 ABIN7254322
发货至: 中国

Quick Overview for NOTCH4 抗体 (ABIN7254322)

抗原

See all NOTCH4 抗体
NOTCH4 (Notch 4 (NOTCH4))

适用

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宿主

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克隆类型

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多克隆

标记

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This NOTCH4 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Antigen affinity purification

    免疫原

    Synthetic peptide of human NOTCH4

    亚型

    IgG
  • 应用备注

    WB 1:800-1:2000, IHC 1:30-1:150, ELISA 1:5000-1:10000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.9 mg/mL

    缓冲液

    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    NOTCH4 (Notch 4 (NOTCH4))

    别名

    NOTCH4

    背景

    This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play a role in vascular, renal and hepatic development. This gene may be associated with susceptibility to schizophrenia in a small portion of cases. An alternative splice variant has been described but its biological nature has not been determined.

    分子量

    Observed_MW: Refer to figures

    Calculated_MW: 210 kDa

    UniProt

    Q99466

    途径

    Notch Signaling
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