CBFB 抗体
Quick Overview for CBFB 抗体 (ABIN7252390)
抗原
See all CBFB 抗体适用
宿主
克隆类型
标记
应用范围
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产品特性
- Polyclonal Antibody
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纯化方法
- Antigen affinity purification
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免疫原
- Full length fusion protein
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亚型
- IgG
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anti-Core-Binding Factor, beta Subunit (CBFB) (AA 1-187) antibody
CBFB 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Core-Binding Factor, beta Subunit (CBFB) (Internal Region) antibodyCBFB 适用: 人 ELISA, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Core-Binding Factor, beta Subunit (CBFB) (N-Term) antibodyCBFB 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Core-Binding Factor, beta Subunit (CBFB) (AA 1-182) antibodyCBFB 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Core-Binding Factor, beta Subunit (CBFB) (AA 61-90) antibodyCBFB 适用: 人, 小鼠 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB21198 unconjugated
anti-Core-Binding Factor, beta Subunit (CBFB) (AA 1-182) antibodyCBFB 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Core-Binding Factor, beta Subunit (CBFB) (AA 1-182) antibodyCBFB 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, FACS, ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Core-Binding Factor, beta Subunit (CBFB) (AA 74-163) antibodyCBFB 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Core-Binding Factor, beta Subunit (CBFB) antibodyCBFB 适用: 人 WB, ICC, DB 宿主: 小鼠 Monoclonal 344C3a unconjugated
anti-Core-Binding Factor, beta Subunit (CBFB) (N-Term) antibodyCBFB 适用: 人, 斑马鱼, Pig WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:30-1:150, ELISA 1:5000-1:10000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.6 mg/mL
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缓冲液
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- CBFB (Core-Binding Factor, beta Subunit (CBFB))
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别名
- CBFB
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背景
- The protein encoded by this gene is the beta subunit of a heterodimeric core-binding transcription factor belonging to the PEBP2/CBF transcription factor family which master-regulates a host of genes specific to hematopoiesis (e.g., RUNX1) and osteogenesis (e.g., RUNX2). The beta subunit is a non-DNA binding regulatory subunit, it allosterically enhances DNA binding by alpha subunit as the complex binds to the core site of various enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers and GM-CSF promoters. Alternative splicing generates two mRNA variants, each encoding a distinct carboxyl terminus. In some cases, a pericentric inversion of chromosome 16 [inv(16)(p13q22)] produces a chimeric transcript consisting of the N terminus of core-binding factor beta in a fusion with the C-terminal portion of the smooth muscle myosin heavy chain 11. This chromosomal rearrangement is associated with acute myeloid leukemia of the M4Eo subtype. Two transcript variants encoding different isoforms have been found for this gene.
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分子量
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Observed_MW: Refer to figures
Calculated_MW: 22 kDa
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UniProt
- Q13951
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途径
- Regulation of Lipid Metabolism by PPARalpha
抗原
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