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ZBTB33 抗体

The 兔 多克隆 anti-ZBTB33 antibody is suitable to detect ZBTB33 in samples from 人. It has been validated for ELISA 和 IHC.
产品编号 ABIN7251583
发货至: 中国
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北京 101111
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for ZBTB33 抗体 (ABIN7251583)

抗原

See all ZBTB33 抗体
ZBTB33 (Zinc Finger and BTB Domain Containing 33 (ZBTB33))

适用

  • 27
  • 12
  • 8
  • 8
  • 5
  • 5
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1

宿主

  • 24
  • 4

克隆类型

  • 20
  • 8
多克隆

标记

  • 24
  • 2
  • 1
  • 1
This ZBTB33 antibody is un-conjugated

应用范围

  • 21
  • 12
  • 7
  • 5
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
ELISA, Immunohistochemistry (IHC)
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Antigen affinity purification

    免疫原

    Synthetic peptide of human ZBTB33

    亚型

    IgG
  • 应用备注

    IHC 1:40-1:200, ELISA 1:5000-1:10000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.9 mg/mL

    缓冲液

    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    ZBTB33 (Zinc Finger and BTB Domain Containing 33 (ZBTB33))

    别名

    ZBTB33

    背景

    This gene encodes a transcriptional regulator with bimodal DNA-binding specificity, which binds to methylated CGCG and also to the non-methylated consensus KAISO-binding site TCCTGCNA. The protein contains an N-terminal POZ/BTB domain and 3 C-terminal zinc finger motifs. It recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters. It may contribute to the repression of target genes of the Wnt signaling pathway, and may also activate transcription of a subset of target genes by the recruitment of catenin delta-2 (CTNND2). Its interaction with catenin delta-1 (CTNND1) inhibits binding to both methylated and non-methylated DNA. It also interacts directly with the nuclear import receptor Importin-α,2 (also known as karyopherin alpha2 or RAG cohort 1), which may mediate nuclear import of this protein. Alternatively spliced transcript variants encoding the same protein have been identified.

    UniProt

    Q86T24
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