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RYR2 抗体

This anti-RYR2 antibody is a 兔 多克隆 antibody detecting RYR2 in ELISA, WB, IF 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7251385
发货至: 中国

Quick Overview for RYR2 抗体 (ABIN7251385)

抗原

See all RYR2 抗体
RYR2 (Ryanodine Receptor 2 (Cardiac) (RYR2))

适用

  • 32
  • 18
  • 18
  • 3
人, 小鼠, 大鼠

宿主

  • 30
  • 2

克隆类型

  • 30
  • 2
多克隆

标记

  • 21
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This RYR2 antibody is un-conjugated

应用范围

  • 15
  • 14
  • 13
  • 9
  • 5
  • 5
  • 5
  • 2
  • 2
ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Affinity purification

    免疫原

    Synthesized peptide derived from human RyR-2 around the non-phosphorylation site of Ser2808.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:5000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    RYR2 (Ryanodine Receptor 2 (Cardiac) (RYR2))

    别名

    RYR2

    背景

    This gene encodes a ryanodine receptor found in cardiac muscle sarcoplasmic reticulum. The encoded protein is one of the components of a calcium channel, composed of a tetramer of the ryanodine receptor proteins and a tetramer of FK506 binding protein 1B proteins, that supplies calcium to cardiac muscle. Mutations in this gene are associated with stress-induced polymorphic ventricular tachycardia and arrhythmogenic right ventricular dysplasia.RYR2 (Ryanodine Receptor 2) is a Protein Coding gene. Diseases associated with RYR2 include Ventricular Tachycardia, Catecholaminergic Polymorphic, 1 and Arrhythmogenic Right Ventricular Dysplasia 2. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds and Cell-type Dependent Selectivity of CCK2R Signaling. GO annotations related to this gene include calcium ion binding and protein kinase binding. An important paralog of this gene is RYR3.

    分子量

    Observed_MW: 200-300 kDa

    Calculated_MW: 564 kDa

    UniProt

    Q92736

    途径

    Myometrial Relaxation and Contraction
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