HDAC5 抗体 (pSer498)
Quick Overview for HDAC5 抗体 (pSer498) (ABIN7250734)
抗原
See all HDAC5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer498
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产品特性
- Phosphorylated antibody
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纯化方法
- Affinity purification
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免疫原
- Synthesized peptide derived from human HDAC5 around the phosphorylation site of Ser498
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亚型
- IgG
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应用备注
- WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:20000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- HDAC5 (Histone Deacetylase 5 (HDAC5))
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别名
- HDAC5
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背景
- Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors.
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分子量
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Observed_MW: 122 kDa
Calculated_MW: 122 kDa
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UniProt
- Q9UQL6
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途径
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Monocarboxylic Acid Catabolic Process
抗原
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