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MMP2 抗体

This anti-MMP2 antibody is a 小鼠 单克隆 antibody detecting MMP2 in IHC (p). Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN7250629
发货至: 中国

Quick Overview for MMP2 抗体 (ABIN7250629)

抗原

See all MMP2 抗体
MMP2 (Matrix Metalloproteinase 2 (MMP2))

适用

  • 175
  • 86
  • 72
  • 53
  • 8
  • 5
  • 5
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  • 2
  • 2
人, 大鼠, 小鼠

宿主

  • 149
  • 55
  • 1
小鼠

克隆类型

  • 137
  • 68
单克隆

标记

  • 114
  • 14
  • 14
  • 9
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This MMP2 antibody is un-conjugated

应用范围

  • 166
  • 66
  • 62
  • 56
  • 41
  • 39
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  • 35
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  • 26
  • 18
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

1H1
  • 产品特性

    Monoclonal Antibody

    纯化方法

    Protein A purification

    免疫原

    Synthetic Peptide of MMP2

    亚型

    IgG
  • 应用备注

    IHC 1:100-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    MMP2 (Matrix Metalloproteinase 2 (MMP2))

    别名

    MMP2

    背景

    Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. As well as degrading extracellular matrix proteins, can also act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction. Also cleaves KISS at a Gly-Leu bond. Appears to have a role in myocardial cell death pathways. Contributes to myocardial oxidative stress by regulating the activity of GSK3beta. Cleaves GSK3beta in vitro.PEX, the C-terminal non-catalytic fragment of MMP2, posseses anti-angiogenic and anti-tumor properties and inhibits cell migration and cell adhesion to FGF2 and vitronectin. Ligand for integrinv/beta3 on the surface of blood vessels.

    UniProt

    P08253

    途径

    Activation of Innate immune Response
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