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Caspase 3 抗体

This anti-Caspase 3 antibody is a 小鼠 单克隆 antibody detecting Caspase 3 in IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7250536
发货至: 中国

Quick Overview for Caspase 3 抗体 (ABIN7250536)

抗原

See all Caspase 3 (CASP3) 抗体
Caspase 3 (CASP3)

适用

  • 217
  • 126
  • 85
  • 18
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  • 8
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  • 3
  • 3
  • 2
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人, 小鼠, 大鼠

宿主

  • 244
  • 27
  • 3
  • 2
  • 2
小鼠

克隆类型

  • 225
  • 52
单克隆

标记

  • 175
  • 21
  • 21
  • 7
  • 7
  • 5
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
This Caspase 3 antibody is un-conjugated

应用范围

  • 214
  • 135
  • 101
  • 65
  • 61
  • 53
  • 48
  • 36
  • 29
  • 27
  • 25
  • 10
  • 10
  • 6
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

4B8
  • 产品特性

    Monoclonal Antibody

    纯化方法

    Protein A purification

    免疫原

    Synthetic Peptide of Caspase-3

    亚型

    IgG
  • 应用备注

    IHC 1:100-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    Caspase 3 (CASP3)

    别名

    CASP3

    背景

    Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin.

    UniProt

    P42574

    途径

    Apoptosis, Caspase Cascade in Apoptosis, Sensory Perception of Sound, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation
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