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NBR1 抗体

This anti-NBR1 antibody is a 小鼠 单克隆 antibody detecting NBR1 in IF 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7250371
发货至: 中国

Quick Overview for NBR1 抗体 (ABIN7250371)

抗原

See all NBR1 抗体
NBR1 (Neighbor of BRCA1 Gene 1 (NBR1))

适用

  • 20
  • 7
  • 5
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 15
  • 7
小鼠

克隆类型

  • 18
  • 4
单克隆

标记

  • 22
This NBR1 antibody is un-conjugated

应用范围

  • 19
  • 10
  • 6
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

4C6
  • 产品特性

    Monoclonal Antibody

    纯化方法

    Protein A purification

    免疫原

    Recombinant Protein of NBR1

    亚型

    IgG
  • 应用备注

    IHC 1:50-300, IF 1:50-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.4.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    NBR1 (Neighbor of BRCA1 Gene 1 (NBR1))

    别名

    NBR1

    背景

    The protein encoded by this gene was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B-box/coiled-coil motif, which is present in many genes with transformation potential. It functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. This gene is located on a region of chromosome 17q21.1 that is in close proximity to the BRCA1 tumor suppressor gene. Alternative splicing of this gene results in multiple transcript variants.NBR1 (NBR1, Autophagy Cargo Receptor) is a Protein Coding gene. Diseases associated with NBR1 include Inclusion Body Myositis and Synucleinopathy. Among its related pathways are Mitophagy - animal. GO annotations related to this gene include ubiquitin binding and mitogen-activated protein kinase binding.

    UniProt

    Q14596

    途径

    Autophagy
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