Active CASP3 抗体
The 小鼠 单克隆 anti-Active CASP3 antibody (Clone 5A2) (ABIN7250272) specifically detects Active CASP3 in IF, IHC (p) 和 WB.
The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7250272
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
Quick Overview for Active CASP3 抗体 (ABIN7250272)
抗原
Active CASP3
适用
人, 小鼠, 大鼠
宿主
小鼠
克隆类型
单克隆
标记
非结合性
应用范围
Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
克隆位点
5A2
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产品特性
- Monoclonal Antibody
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纯化方法
- Protein A purification
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免疫原
- Recombinant Protein
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亚型
- IgG
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anti-Active CASP3 (active) antibody
适用: 人, 小鼠, 大鼠 IF, IHC (p), WB 宿主: 小鼠 Monoclonal 5A2 unconjugated
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应用备注
- WB 1:500-1:1000, IHC 1:100-1:200, IF 1:100-1:200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.4.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- Active CASP3
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背景
- Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin.
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分子量
- 17 kDa
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UniProt
- P42574
抗原
-
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