Active CASP3 (active) 抗体
The 小鼠 单克隆 anti-Active CASP3 antibody (Clone 5A2) (ABIN5955568) specifically detects Active CASP3 in IF, IHC (p) 和 WB.
The antibody is reactive with 人, 小鼠 和 大鼠 samples.
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产品编号 ABIN5955568
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
Quick Overview for Active CASP3 (active) 抗体 (ABIN5955568)
抗原
Active CASP3
适用
人, 小鼠, 大鼠
宿主
小鼠
克隆类型
单克隆
标记
非结合性
应用范围
Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
克隆位点
5A2
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抗原表位
- active
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特异性
- A830040C14Rik,Apopain,CASP-3,CASP3,CASP3,Casp3a,Caspase 3,Caspase 3,apoptosis-related cysteine peptidase,Caspase 3,apoptosis-related cysteine protease,Caspase 3,apoptosis-related cysteine protease a,Caspase-3 subunit p12,CC3,CPP-32,CPP32,CPP32B,Cysteine protease CPP32,EC 3.4.22.56,LICE,mldy,OTTHUMP00000165052,OTTHUMP00000165053,OTTHUMP00000165054,PARP cleavage protease,Procaspase3,Protein Yama,SCA 1,SCA-1,SREBP cleavage activity 1,Yama
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纯化方法
- Protein A purification
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免疫原
- Recombinant Protein
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亚型
- IgG
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anti-Active CASP3 antibody
适用: 人, 小鼠, 大鼠 IF, IHC (p), WB 宿主: 小鼠 Monoclonal 5A2 unconjugated
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应用备注
- WB 1:500-1:1000, IHC 1:100-1:200, IF 1:100-1:200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.4.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- Active CASP3
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背景
- Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin.
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基因ID
- 836
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UniProt
- P42574
抗原
-
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