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MICU1 抗体

The 小鼠 单克隆 anti-MICU1 antibody is suitable to detect MICU1 in samples from 人, 大鼠 和 小鼠. It has been validated for WB, IHC (p) 和 IF.
产品编号 ABIN7250269
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for MICU1 抗体 (ABIN7250269)

抗原

See all MICU1 抗体
MICU1 (Mitochondrial Calcium Uptake 1 (MICU1))

适用

  • 33
  • 9
  • 8
  • 2
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  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
人, 大鼠, 小鼠

宿主

  • 26
  • 7
  • 1
小鼠

克隆类型

  • 28
  • 6
单克隆

标记

  • 17
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
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  • 1
  • 1
  • 1
This MICU1 antibody is un-conjugated

应用范围

  • 23
  • 14
  • 5
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

克隆位点

4E7
  • 产品特性

    Monoclonal Antibody

    纯化方法

    Protein A purification

    免疫原

    Recombinant Protein

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, IHC 1:100-1:200, IF 1:100-1:300

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.4.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    MICU1 (Mitochondrial Calcium Uptake 1 (MICU1))

    别名

    MICU1

    背景

    This gene encodes an essential regulator of mitochondrial Ca2+ uptake under basal conditions. The encoded protein interacts with the mitochondrial calcium uniporter, a mitochondrial inner membrane Ca2+ channel, and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of reactive oxygen species and cell stress. Alternatively spliced transcript variants encoding different isoforms have been described. MICU1 (Mitochondrial Calcium Uptake 1) is a Protein Coding gene. Diseases associated with MICU1 include Myopathy With Extrapyramidal Signs and Fish Allergy. Among its related pathways are Ca, cAMP and Lipid Signaling. GO annotations related to this gene include calcium ion binding and protein heterodimerization activity. An important paralog of this gene is MICU3.

    分子量

    55 kDa

    UniProt

    Q9BPX6
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