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Histone H2B 抗体

This anti-Histone H2B antibody is a 小鼠 单克隆 antibody detecting Histone H2B in WB 和 IF. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7250209
发货至: 中国

Quick Overview for Histone H2B 抗体 (ABIN7250209)

抗原

See all Histone H2B 抗体
Histone H2B

适用

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人, 小鼠, 大鼠

宿主

  • 218
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  • 2
小鼠

克隆类型

  • 209
  • 32
单克隆

标记

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This Histone H2B antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF)

克隆位点

3C3
  • 产品特性

    Monoclonal Antibody

    纯化方法

    Protein A purification

    免疫原

    Synthetic Peptide

    亚型

    IgG
  • 应用备注

    WB 1:1000-3000, IF 1:100-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.4.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    Histone H2B

    背景

    Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2B family. Transcripts from this gene lack polyA tails, instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3. HIST1H2BB (Histone Cluster 1 H2B Family Member B) is a Protein Coding gene. Among its related pathways are DNA Double-Strand Break Repair and Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3. GO annotations related to this gene include sequence-specific DNA binding and protein heterodimerization activity. An important paralog of this gene is HIST1H2BN.

    分子量

    Observed_MW: 14 kDa

    Calculated_MW: 14 kDa

    UniProt

    P33778
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