KIF7 抗体
Quick Overview for KIF7 抗体 (ABIN7250092)
抗原
See all KIF7 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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产品特性
- Monoclonal Antibody
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纯化方法
- Protein A purification
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免疫原
- Synthetic Peptide
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亚型
- IgG
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anti-Kinesin Family Member 7 (KIF7) antibody
KIF7 适用: 人, 小鼠, 大鼠 WB, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Kinesin Family Member 7 (KIF7) antibodyKIF7 适用: 人 ELISA, IHC 宿主: 小鼠 Monoclonal unconjugated
anti-Kinesin Family Member 7 (KIF7) antibodyKIF7 适用: 人, 小鼠, 大鼠 IHC 宿主: 小鼠 Monoclonal 3F8 unconjugated
anti-Kinesin Family Member 7 (KIF7) (AA 1224-1273) antibodyKIF7 适用: 人, Cow, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Kinesin Family Member 7 (KIF7) (AA 1044-1343) antibodyKIF7 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- IHC 1:100-1:300, IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.4.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- KIF7 (Kinesin Family Member 7 (KIF7))
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别名
- KIF7
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背景
- This gene encodes a cilia-associated protein belonging to the kinesin family. This protein plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in this gene have been associated with various ciliopathies.KIF7 (Kinesin Family Member 7) is a Protein Coding gene. Diseases associated with KIF7 include Acrocallosal Syndrome and Hydrolethalus Syndrome 2. Among its related pathways are Signaling by Hedgehog and Signaling by GPCR. GO annotations related to this gene include ATPase activity and microtubule motor activity. An important paralog of this gene is KIF27.
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UniProt
- Q2M1P5
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途径
- Hedgehog Signaling
抗原
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