电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

Laminin beta 1 抗体

The 兔 多克隆 anti-Laminin beta 1 antibody (ABIN7249926) specifically detects Laminin beta 1 in WB. The antibody is reactive with 小鼠 和 大鼠 samples.
产品编号 ABIN7249926
发货至: 中国
Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Laminin beta 1 抗体 (ABIN7249926)

抗原

See all Laminin beta 1 (LAMB1) 抗体
Laminin beta 1 (LAMB1) (Laminin, beta 1 (LAMB1))

适用

  • 56
  • 40
  • 24
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
小鼠, 大鼠

宿主

  • 54
  • 7

克隆类型

  • 35
  • 26
多克隆

标记

  • 25
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
This Laminin beta 1 antibody is un-conjugated

应用范围

  • 39
  • 22
  • 17
  • 11
  • 9
  • 7
  • 7
  • 4
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Affinity purification

    免疫原

    Recombinant protein corresponding to Mouse Laminin beta1

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.2 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 1 % BSA and 50 % glycerol, pH 7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    Laminin beta 1 (LAMB1) (Laminin, beta 1 (LAMB1))

    别名

    Laminin beta1

    背景

    Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins are composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively) and they form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Each laminin chain is a multidomain protein encoded by a distinct gene. Several isoforms of each chain have been described. This gene encodes the beta chain isoform laminin, beta 1. The beta 1 chain has 7 structurally distinct domains which it shares with other beta chain isomers. The C-terminal helical region containing domains I and II are separated by domain alpha, domains III and V contain several EGF-like repeats, and domains IV and VI have a globular conformation. Laminin, beta 1 is expressed in most tissues that produce basement membranes, and is one of the 3 chains constituting laminin 1, the first laminin isolated from Engelbreth-Holm-Swarm (EHS) tumor. A sequence in the beta 1 chain that is involved in cell attachment, chemotaxis, and binding to the laminin receptor was identified and shown to have the capacity to inhibit metastasis.

    分子量

    Observed_MW: 220 kDa

    Calculated_MW: 198 kDa

    UniProt

    P07942, P02469
You are here: