Laminin beta 1 抗体
Quick Overview for Laminin beta 1 抗体 (ABIN7249926)
抗原
See all Laminin beta 1 (LAMB1) 抗体适用
宿主
克隆类型
标记
应用范围
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产品特性
- Polyclonal Antibody
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纯化方法
- Affinity purification
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免疫原
- Recombinant protein corresponding to Mouse Laminin beta1
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亚型
- IgG
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anti-Laminin, beta 1 (LAMB1) antibody
LAMB1 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Laminin, beta 1 (LAMB1) (AA 1053-1258) antibodyLAMB1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Laminin, beta 1 (LAMB1) (C-Term) antibodyLAMB1 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Laminin, beta 1 (LAMB1) (C-Term) antibodyLAMB1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Laminin, beta 1 (LAMB1) (C-Term) antibodyLAMB1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Laminin, beta 1 (LAMB1) (AA 31-270) antibodyLAMB1 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal 2D9G5 unconjugated
anti-Laminin, beta 1 (LAMB1) (AA 1-1786) antibodyLAMB1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Laminin, beta 1 (LAMB1) (Middle Region) antibodyLAMB1 适用: 人, 小鼠, 大鼠, 兔, 犬, 豚鼠, 马, Cow, Pig, Saccharomyces cerevisiae WB 宿主: 兔 Polyclonal unconjugated
anti-Laminin, beta 1 (LAMB1) (AA 1721-1770) antibodyLAMB1 适用: 人, 小鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Laminin, beta 1 (LAMB1) (AA 523-661) antibodyLAMB1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.2 mg/mL
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缓冲液
- PBS with 0.02 % sodium azide, 1 % BSA and 50 % glycerol, pH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- Laminin beta 1 (LAMB1) (Laminin, beta 1 (LAMB1))
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别名
- Laminin beta1
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背景
- Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins are composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively) and they form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Each laminin chain is a multidomain protein encoded by a distinct gene. Several isoforms of each chain have been described. This gene encodes the beta chain isoform laminin, beta 1. The beta 1 chain has 7 structurally distinct domains which it shares with other beta chain isomers. The C-terminal helical region containing domains I and II are separated by domain alpha, domains III and V contain several EGF-like repeats, and domains IV and VI have a globular conformation. Laminin, beta 1 is expressed in most tissues that produce basement membranes, and is one of the 3 chains constituting laminin 1, the first laminin isolated from Engelbreth-Holm-Swarm (EHS) tumor. A sequence in the beta 1 chain that is involved in cell attachment, chemotaxis, and binding to the laminin receptor was identified and shown to have the capacity to inhibit metastasis.
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分子量
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Observed_MW: 220 kDa
Calculated_MW: 198 kDa
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UniProt
- P07942, P02469
抗原
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