Laminin beta 1 抗体 (C-Term)
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- 抗原 See all Laminin beta 1 (LAMB1) 抗体
- Laminin beta 1 (LAMB1) (Laminin, beta 1 (LAMB1))
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抗原表位
- C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Laminin beta 1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
- 交叉反应
- 人, 小鼠
- 产品特性
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Rabbit Polyclonal antibody to Laminin beta 1 (laminin, beta 1)
Laminin beta 1 antibody - 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Recombinant protein encompassing a sequence within the C-terminus region of human Laminin beta 1. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product LAMB1 Primary Antibody
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anti-Laminin, beta 1 (LAMB1) antibody
LAMB1 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Laminin, beta 1 (LAMB1) (AA 1053-1258) antibodyLAMB1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Laminin, beta 1 (LAMB1) (C-Term) antibodyLAMB1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Laminin, beta 1 (LAMB1) (C-Term) antibodyLAMB1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Laminin, beta 1 (LAMB1) (AA 31-270) antibodyLAMB1 适用: 人 WB, IHC, ELISA 宿主: 小鼠 Monoclonal 2D9G5 unconjugated
anti-Laminin, beta 1 (LAMB1) (AA 1-1786) antibodyLAMB1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Laminin, beta 1 (LAMB1) (AA 652-790) antibodyLAMB1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Laminin, beta 1 (LAMB1) (Middle Region) antibodyLAMB1 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, 兔, Cow, Pig, Saccharomyces cerevisiae WB 宿主: 兔 Polyclonal unconjugated
anti-Laminin, beta 1 (LAMB1) (AA 1721-1770) antibodyLAMB1 适用: 人, 小鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Laminin, beta 1 (LAMB1) (AA 523-661) antibodyLAMB1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Positive Control: NIH-3T3
Validation: Orthogonal
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.65 mg/mL
- 缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- 抗原
- Laminin beta 1 (LAMB1) (Laminin, beta 1 (LAMB1))
- 别名
- laminin subunit beta 1 (LAMB1 产品)
- 别名
- CLM antibody, LIS5 antibody, fc20b05 antibody, gup antibody, lamb1 antibody, sb:cb95 antibody, wu:fc20b05 antibody, Lamb1-1 antibody, LAMB1 antibody, C77966 antibody, C80098 antibody, C81607 antibody, D130003D08Rik antibody, Lamb-1 antibody, laminin subunit beta 1 antibody, laminin, beta 1a antibody, laminin B1 antibody, LAMB1 antibody, lamb1a antibody, Lamb1 antibody, lamb1 antibody
- 背景
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Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins are composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively) and they form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Each laminin chain is a multidomain protein encoded by a distinct gene. Several isoforms of each chain have been described. Different alpha, beta and gamma chain isomers combine to give rise to different heterotrimeric laminin isoforms which are designated by Arabic numerals in the order of their discovery, i.e. alpha1beta1gamma1 heterotrimer is laminin 1. The biological functions of the different chains and trimer molecules are largely unknown, but some of the chains have been shown to differ with respect to their tissue distribution, presumably reflecting diverse functions in vivo. This gene encodes the beta chain isoform laminin, beta 1. The beta 1 chain has 7 structurally distinct domains which it shares with other beta chain isomers. The C-terminal helical region containing domains I and II are separated by domain alpha, domains III and V contain several EGF-like repeats, and domains IV and VI have a globular conformation. Laminin, beta 1 is expressed in most tissues that produce basement membranes, and is one of the 3 chains constituting laminin 1, the first laminin isolated from Engelbreth-Holm-Swarm (EHS) tumor. A sequence in the beta 1 chain that is involved in cell attachment, chemotaxis, and binding to the laminin receptor was identified and shown to have the capacity to inhibit metastasis.
Cellular Localization: Secreted , extracellular space , extracellular matrix , basement membrane - 分子量
- 198 kDa
- 基因ID
- 3912
- UniProt
- P07942
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