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ACTN1 抗体

This anti-ACTN1 antibody is a 兔 多克隆 antibody detecting ACTN1 in WB. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7249742
发货至: 中国

Quick Overview for ACTN1 抗体 (ABIN7249742)

抗原

See all ACTN1 抗体
ACTN1 (Actinin, alpha 1 (ACTN1))

适用

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人, 小鼠, 大鼠

宿主

  • 46
  • 11
  • 1

克隆类型

  • 48
  • 10
多克隆

标记

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This ACTN1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Affinity purification

    免疫原

    Recombinant protein corresponding to Mousealpha-actinin1

    亚型

    IgG
  • 应用备注

    WB 1:1000-1:3000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.66 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 1 % BSA and 50 % glycerol, pH 7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    ACTN1 (Actinin, alpha 1 (ACTN1))

    别名

    ACTN1

    背景

    Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene.

    分子量

    Observed_MW: 110 kDa

    Calculated_MW: 102-107 kDa

    UniProt

    P12814, Q7TPR4, Q9Z1P2

    途径

    Cell-Cell Junction Organization
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