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Paxillin 抗体 (AA 501-591) (HRP)

PXN 适用: 人, 小鼠 WB, ELISA, IHC (p), IHC (fro) 宿主: 兔 Polyclonal HRP
产品编号 ABIN700504
发货至: 中国
  • 抗原 See all Paxillin (PXN) 抗体
    Paxillin (PXN)
    抗原表位
    • 32
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    • 9
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    AA 501-591
    适用
    • 208
    • 103
    • 73
    • 15
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    • 5
    • 4
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    • 3
    • 1
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    • 1
    人, 小鼠
    宿主
    • 201
    • 25
    • 1
    克隆类型
    • 184
    • 43
    多克隆
    标记
    • 119
    • 10
    • 6
    • 6
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    This Paxillin antibody is conjugated to HRP
    应用范围
    • 162
    • 61
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    • 37
    • 26
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    • 17
    • 15
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    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    人, 小鼠
    预测反应
    Rat,Dog,Cow,Horse,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human Paxillin
    亚型
    IgG
    Top Product
    Discover our top product PXN Primary Antibody
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    注意事项
    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    Paxillin (PXN)
    别名
    Paxillin (PXN 产品)
    背景

    Synonyms: Paired box protein Pax 1, PAX 1, PAX1, Paxillin alpha, PXN, PXN protein, FLJ16691, FLJ23042, FLJ16691, PAXI_HUMAN, Paxillin, PXN protein.

    Background: Paxillin is a 64 kDa cytoskeletal adapter protein involved in organisation and function of focal adhesions, which are critical to cell adhesion and migration. This in turn plays a role in a wide variety of processes including embryogenesis, organogenesis, wound repair, inflammation and cancer. Paxillin contains LD motifs, LIM domains, SH3 and SH2 binding domains that serve as docking sites for cytoskeletal proteins, tyrosine kinases (e.g., FAK, Pyk 2, Src), serine/threonine kinases, GTPase activating proteins and other adaptor proteins (e.g., Actin, Vinculin, Crk).

    基因ID
    5829
    途径
    MAPK Pathway, EGFR Signaling Pathway, Response to Growth Hormone Stimulus, Cell-Cell Junction Organization, Maintenance of Protein Location, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
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