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MOB2 抗体

MOB2 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7248908
发货至: 中国
  • 抗原 See all MOB2 抗体
    MOB2 (MOB Kinase Activator 2 (MOB2))
    适用
    • 28
    • 17
    • 1
    人, 小鼠
    宿主
    • 24
    • 3
    • 1
    克隆类型
    • 26
    • 2
    多克隆
    标记
    • 11
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MOB2 antibody is un-conjugated
    应用范围
    • 21
    • 14
    • 14
    • 14
    • 3
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    产品特性
    Polyclonal Antibody
    纯化方法
    Antigen affinity purification
    免疫原
    Synthetic peptide of human MOB2
    亚型
    IgG
    Top Product
    Discover our top product MOB2 Primary Antibody
  • 应用备注
    IHC 1:40-1:200, ELISA 1:5000-1:10000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.08 mg/mL
    缓冲液
    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    MOB2 (MOB Kinase Activator 2 (MOB2))
    别名
    MOB2 (MOB2 产品)
    别名
    HCCA2 antibody, 1110017M21Rik antibody, 2700078K21Rik antibody, AI256456 antibody, Mmh antibody, Hcca2 antibody, RGD1562983 antibody, hcca2 antibody, mob2 antibody, mob2.1 antibody, p5a5 antibody, Mob2 antibody, MOB kinase activator 2 antibody, MOB kinase activator 2 L homeolog antibody, multigenic obesity QTL 2 antibody, MOB2 antibody, Mob2 antibody, mob2.1.L antibody, Mobq2 antibody
    背景
    MOB2 (Mps one binder kinase activator-like 2), also known as HCCA2 (Hepatocellular carcinoma-associated gene 2), is a 467 amino acid protein that belongs to the MOB1/phocein family. MOB2 is expressed in lung, spleen, brain, and fetal liver. It is highly expressed in hepatocellular carcinoma. MOB2 is localized in the perinuclear region of the cytoplasm in liver cancer tissues and colocalizes with MAD2L2 in the nucleus of Hela cells. MOB2 is characterized by two N-glycosylation sites, six N-myristolylation sites, two Src homology 3 (SH3), and several phosphorylation motifs which indicate that this protein may play a role in an intracellular signal transduction cascade. MOB2 binds to and regulates the autophosphorylation of the related human serine/threonine kinase 38 (NDR1) and serine/threonine kinase 38L(NDR2). It has been shown that MOB2 plays a critical role in cell cycle regulation. Overexpression of the protein during the G0/G1 phase inhibits cell proliferation causing cell cycle arrest. Stimulates the autophosphorylation and kinase activity of STK38 and STK38L.
    UniProt
    Q70IA6
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