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IRG1 抗体

This anti-IRG1 antibody is a 兔 多克隆 antibody detecting IRG1 in ELISA 和 WB. Suitable for 人 和 小鼠.
产品编号 ABIN7248602
发货至: 中国

Quick Overview for IRG1 抗体 (ABIN7248602)

抗原

IRG1 (Immunoresponsive Gene 1 (IRG1))

适用

人, 小鼠

宿主

  • 7

克隆类型

  • 7
多克隆

标记

  • 3
  • 2
  • 1
  • 1
This IRG1 antibody is un-conjugated

应用范围

  • 6
  • 2
  • 1
  • 1
  • 1
ELISA, Western Blotting (WB)
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Antigen affinity purification

    免疫原

    Synthetic peptide of human ACOD1

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, ELISA 1:5000-1:10000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.32 mg/mL

    缓冲液

    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    IRG1 (Immunoresponsive Gene 1 (IRG1))

    别名

    ACOD1

    背景

    Involved in the inhibition of the inflammatory response. Acts as a negative regulator of the Toll-like receptors (TLRs)-mediated inflammatory innate response by stimulating the tumor necrosis factor alpha-induced protein TNFAIP3 expression via reactive oxygen species (ROS) in LPS-tolerized macrophages. Involved in antimicrobial response of innate immune cells, ACOD1-mediated itaconic acid production contributes to the antimicrobial activity of macrophages. Plays a role in the embryo implantation.

    分子量

    Observed_MW: Refer to figures

    Calculated_MW: 53 kDa

    UniProt

    A6NK06
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