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GLI1 抗体

This anti-GLI1 antibody is a 兔 多克隆 antibody detecting GLI1 in WB, ELISA 和 IHC. Suitable for 人 和 小鼠.
产品编号 ABIN7248113
发货至: 中国

Quick Overview for GLI1 抗体 (ABIN7248113)

抗原

See all GLI1 抗体
GLI1 (Zinc Finger Protein GLI1 (GLI1))

适用

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人, 小鼠

宿主

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  • 1

克隆类型

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多克隆

标记

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  • 1
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This GLI1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Antigen affinity purification

    免疫原

    Synthetic peptide of human GLI1

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, IHC 1:50-1:100, ELISA 1:5000-1:10000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.08 mg/mL

    缓冲液

    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    GLI1 (Zinc Finger Protein GLI1 (GLI1))

    别名

    GLI1

    背景

    GLI1 (GLI Family Zinc Finger 1) is a Protein Coding gene. Diseases associated with GLI1 include Basal Cell Carcinoma and Necrobiosis Lipoidica. Among its related pathways are Wnt Signaling Pathways: beta-Catenin-independent Wnt/Ca2+ Signaling and Other Non-canonical Wnt Signaling Pathways and G-Beta Gamma Signaling. GO annotations related to this gene include chromatin binding and microtubule binding. An important paralog of this gene is GLI2. This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene.

    分子量

    Observed_MW: Refer to figures

    Calculated_MW: 118 kDa

    UniProt

    P08151

    途径

    Hedgehog Signaling, Dopaminergic Neurogenesis
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