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SAV1 抗体

This anti-SAV1 antibody is a 兔 多克隆 antibody detecting SAV1 in ELISA 和 IHC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7247840
发货至: 中国

Quick Overview for SAV1 抗体 (ABIN7247840)

抗原

See all SAV1 抗体
SAV1 (Salvador Homolog 1 (SAV1))

适用

  • 27
  • 5
  • 4
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 21
  • 6
  • 1

克隆类型

  • 25
  • 3
多克隆

标记

  • 23
  • 1
  • 1
  • 1
  • 1
  • 1
This SAV1 antibody is un-conjugated

应用范围

  • 26
  • 16
  • 9
  • 7
  • 5
  • 2
  • 1
ELISA, Immunohistochemistry (IHC)
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Antigen affinity purification

    免疫原

    Fusion protein of human SAV1

    亚型

    IgG
  • 应用备注

    IHC 1:100-1:300, ELISA 1:5000-1:10000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.32 mg/mL

    缓冲液

    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    SAV1 (Salvador Homolog 1 (SAV1))

    别名

    SAV1

    背景

    WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein with two WW domains, a SARAH domain, and a coiled-coil region and is ubiquitously expressed in adult tissues. This protein binds to MST1 (mammalian sterile 20-like kinase 1) and promotes MST1-induced apoptosis. It has also been shown to bind to HAX1 (hematopoietic cell-specific protein 1 (HS1)-associated protein X-1) and to attenuate the anti-apoptotic effects of HAX1. Studies in human and mouse suggest this gene acts as a tumor suppressor.

    UniProt

    Q9H4B6

    途径

    Stem Cell Maintenance
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