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PLK1 抗体 (AA 201-300)

This anti-PLK1 antibody is a 兔 多克隆 antibody detecting PLK1 in WB, ELISA, IHC (p), IF (cc), IF (p), ICC 和 IHC (fro). Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN700435
发货至: 中国

Quick Overview for PLK1 抗体 (AA 201-300) (ABIN700435)

抗原

See all PLK1 抗体
PLK1 (Polo-Like Kinase 1 (PLK1))

适用

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宿主

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克隆类型

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多克隆

标记

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This PLK1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
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    AA 201-300

    交叉反应

    预测反应

    Mouse,Rat,Dog,Pig,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human PLK1

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • Gibori, Eliyahu, Krivitsky, Ben-Shushan, Epshtein, Tiram, Blau, Ofek, Lee, Ruppin, Landsman, Barshack, Golan, Merquiol, Blum, Satchi-Fainaro: "Amphiphilic nanocarrier-induced modulation of PLK1 and miR-34a leads to improved therapeutic response in pancreatic cancer." in: Nature communications, Vol. 9, Issue 1, pp. 16, (2018) (PubMed).

  • 抗原

    PLK1 (Polo-Like Kinase 1 (PLK1))

    别名

    PLK1

    背景

    Synonyms: PLK, STPK13, Serine/threonine-protein kinase PLK1, Polo-like kinase 1, PLK-1, Serine/threonine-protein kinase 13, PLK1

    Background: PLK1 (polo-like kinase 1) is a member of the serine/threonine protein kinase family, cdc5/polo subfamily. PLK1 contains two polo box domains with a predicted molecular weight of 68 kDa. PLK1 has been shown to regulate cdc2/cyclin B through phosphorylation and activation of cdc25c phosphatase. PLK1 is modified by phosphorylation at Threonine 210. PLK1 may also be required for cell division. Depletion of PLK1 results in apoptosis and deregulation of expression of PKL1 is correlated with development of many malignancies.

    基因ID

    5347

    UniProt

    P53350

    途径

    Cell Division Cycle, M Phase
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