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EWSR1 抗体

This anti-EWSR1 antibody is a 兔 多克隆 antibody detecting EWSR1 in WB, ELISA 和 IHC. Suitable for 人 和 小鼠.
产品编号 ABIN7247048
发货至: 中国

Quick Overview for EWSR1 抗体 (ABIN7247048)

抗原

See all EWSR1 抗体
EWSR1 (Ewing Sarcoma Breakpoint Region 1 (EWSR1))

适用

  • 72
  • 35
  • 30
  • 11
  • 8
  • 8
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  • 7
  • 6
  • 5
  • 5
  • 3
  • 2
  • 1
人, 小鼠

宿主

  • 60
  • 10
  • 2
  • 1

克隆类型

  • 62
  • 11
多克隆

标记

  • 55
  • 4
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This EWSR1 antibody is un-conjugated

应用范围

  • 63
  • 27
  • 17
  • 15
  • 6
  • 5
  • 5
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Antigen affinity purification

    免疫原

    Fusion protein of human EWSR1

    亚型

    IgG
  • 应用备注

    WB 1:1000-1:5000, IHC 1:50-1:300, ELISA 1:5000-1:10000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.26 mg/mL

    缓冲液

    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    EWSR1 (Ewing Sarcoma Breakpoint Region 1 (EWSR1))

    别名

    EWSR1

    背景

    This gene encodes a multifunctional protein that is involved in various cellular processes, including gene expression, cell signaling, and RNA processing and transport. The protein includes an N-terminal transcriptional activation domain and a C-terminal RNA-binding domain. Chromosomal translocations between this gene and various genes encoding transcription factors result in the production of chimeric proteins that are involved in tumorigenesis. These chimeric proteins usually consist of the N-terminal transcriptional activation domain of this protein fused to the C-terminal DNA-binding domain of the transcription factor protein. Mutations in this gene, specifically a t(11,22)(q24,q12) translocation, are known to cause Ewing sarcoma as well as neuroectodermal and various other tumors. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and 14.

    分子量

    Observed_MW: Refer to figures

    Calculated_MW: 68 kDa

    UniProt

    Q01844
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