IGHA1 抗体
Quick Overview for IGHA1 抗体 (ABIN7246370)
抗原
适用
宿主
克隆类型
标记
应用范围
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产品特性
- Polyclonal Antibody
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纯化方法
- Antigen affinity purification
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免疫原
- Fusion protein of human IGHA1
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亚型
- IgG
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anti-Immunoglobulin Heavy Constant alpha 1 (IGHA1) (AA 207-353) antibody
IGHA1 适用: 人, 猴, 小鼠 IHC, WB, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 7D5F12 unconjugated
anti-Immunoglobulin Heavy Constant alpha 1 (IGHA1) (AA 257-286) antibodyIGHA1 适用: 人 IHC, WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Immunoglobulin Heavy Constant alpha 1 (IGHA1) (AA 257-286), (C-Term) antibodyIGHA1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB18272 unconjugated
anti-Immunoglobulin Heavy Constant alpha 1 (IGHA1) antibodyIGHA1 适用: 人 IHC, WB, FACS 宿主: 兔 Polyclonal unconjugated
anti-Immunoglobulin Heavy Constant alpha 1 (IGHA1) (C-Term) antibodyIGHA1 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- IHC 1:50-1:300, ELISA 1:5000-1:10000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.14 mg/mL
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缓冲液
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- IGHA1 (Immunoglobulin Heavy Constant alpha 1 (IGHA1))
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别名
- IGHA1
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背景
- Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268). Ig alpha is the major immunoglobulin class in body secretions (PubMed:2241915).
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UniProt
- P01876
抗原
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