DENND1B 抗体
Quick Overview for DENND1B 抗体 (ABIN7246211)
抗原
See all DENND1B 抗体适用
宿主
克隆类型
标记
应用范围
-
-
产品特性
- Polyclonal Antibody
-
纯化方法
- Antigen affinity purification
-
免疫原
- Fusion protein of human DENND1B
-
亚型
- IgG
-
-
-
-
应用备注
- WB 1:500-1:2000, ELISA 1:5000-1:10000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.54 mg/mL
-
缓冲液
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- DENND1B (DENN/MADD Domain Containing 1B (DENND1B))
-
别名
- DENND1B
-
背景
- Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1B, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2, see MIM 601024). Thus, connecdenns link RAB35 activation with the clathrin machinery.
-
分子量
-
Observed_MW: Refer to figures
Calculated_MW: 86 kDa
-
UniProt
- Q6P3S1
抗原
-