CEP57 抗体
Quick Overview for CEP57 抗体 (ABIN7246166)
抗原
See all CEP57 抗体适用
宿主
克隆类型
标记
应用范围
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产品特性
- Polyclonal Antibody
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纯化方法
- Antigen affinity purification
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免疫原
- Full length fusion protein
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亚型
- IgG
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anti-Centrosomal Protein 57kDa (CEP57) antibody
CEP57 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Centrosomal Protein 57kDa (CEP57) (AA 1-240) antibodyCEP57 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Centrosomal Protein 57kDa (CEP57) (AA 1-500) antibodyCEP57 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Centrosomal Protein 57kDa (CEP57) (AA 19-128) antibodyCEP57 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1E9 unconjugated
anti-Centrosomal Protein 57kDa (CEP57) (AA 1-500) antibodyCEP57 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Centrosomal Protein 57kDa (CEP57) (Internal Region) antibodyCEP57 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Centrosomal Protein 57kDa (CEP57) (AA 1-240) antibodyCEP57 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Centrosomal Protein 57kDa (CEP57) (AA 19-128) antibodyCEP57 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Centrosomal Protein 57kDa (CEP57) (AA 241-290) antibodyCEP57 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Centrosomal Protein 57kDa (CEP57) (Center) antibodyCEP57 适用: 人, 猴 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, ELISA 1:5000-1:10000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.42 mg/mL
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缓冲液
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- CEP57 (Centrosomal Protein 57kDa (CEP57))
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别名
- CEP57
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背景
- This gene encodes a cytoplasmic protein called Translokin. This protein localizes to the centrosome and has a function in microtubular stabilization. The N-terminal half of this protein is required for its centrosome localization and for its multimerization, and the C-terminal half is required for nucleating, bundling and anchoring microtubules to the centrosomes. This protein specifically interacts with fibroblast growth factor 2 (FGF2), sorting nexin 6, Ran-binding protein M and the kinesins KIF3A and KIF3B, and thus mediates the nuclear translocation and mitogenic activity of the FGF2. It also interacts with cyclin D1 and controls nucleocytoplasmic distribution of the cyclin D1 in quiescent cells. This protein is crucial for maintaining correct chromosomal number during cell division. Mutations in this gene cause mosaic variegated aneuploidy syndrome, a rare autosomal recessive disorder. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
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分子量
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Observed_MW: Refer to figures
Calculated_MW: 57 kDa
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UniProt
- Q86XR8
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途径
- M Phase, Maintenance of Protein Location, Protein targeting to Nucleus, Growth Factor Binding
抗原
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