IFI35 抗体
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北京 101111
Quick Overview for IFI35 抗体 (ABIN7003659)
抗原
See all IFI35 抗体适用
宿主
克隆类型
标记
应用范围
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产品特性
- Polyclonal Antibody
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纯化方法
- Antigen affinity purification
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免疫原
- Synthetic peptide of human IFI35
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亚型
- IgG
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应用备注
- IHC 1:30-1:150, ELISA 1:5000-1:10000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.02 mg/mL
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缓冲液
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- IFI35 (Interferon-Induced Protein 35 (IFI35))
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别名
- IFI35
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背景
- The Interferon family of proteins are able to alter the expression of a variety of target genes, thereby controlling various events within the cell. IFI-35 (Interferon-induced 35 kDa protein), also known as IFP35, is a 286 amino acid interferon-induced protein. Localized to the nucleus and expressed in macrophages, fibroblasts and epithelial cells, IFI-35 is a leucine zipper protein that can form homodimers, but, unlike most leucine zipper proteins, cannot bind DNA. Upon induction by IFN-α, IFI-35 associates with Nmi (N-Myc-interacting protein), resulting in the formation of a high molecular weight complex that is thought to play a role in IFN-α signaling and cellular responses. Once complexed with Nmi, IFI-35 is unable to be degraded by the proteasome, suggesting that IFI-35 is protected from degradation only when needed by IFN-α. Two isoforms of IFI-35 exist due to alternative splicing events.
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UniProt
- P80217
抗原
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