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IFI35 抗体

This anti-IFI35 antibody is a 兔 多克隆 antibody detecting IFI35 in IHC 和 ELISA. Suitable for 人.
产品编号 ABIN7003659
发货至: 中国

Quick Overview for IFI35 抗体 (ABIN7003659)

抗原

See all IFI35 抗体
IFI35 (Interferon-Induced Protein 35 (IFI35))

适用

  • 36
  • 3
  • 2

宿主

  • 27
  • 9

克隆类型

  • 30
  • 6
多克隆

标记

  • 23
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This IFI35 antibody is un-conjugated

应用范围

  • 28
  • 13
  • 11
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
Immunohistochemistry (IHC), ELISA
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Antigen affinity purification

    免疫原

    Synthetic peptide of human IFI35

    亚型

    IgG
  • 应用备注

    IHC 1:30-1:150, ELISA 1:5000-1:10000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.02 mg/mL

    缓冲液

    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    IFI35 (Interferon-Induced Protein 35 (IFI35))

    别名

    IFI35

    背景

    The Interferon family of proteins are able to alter the expression of a variety of target genes, thereby controlling various events within the cell. IFI-35 (Interferon-induced 35 kDa protein), also known as IFP35, is a 286 amino acid interferon-induced protein. Localized to the nucleus and expressed in macrophages, fibroblasts and epithelial cells, IFI-35 is a leucine zipper protein that can form homodimers, but, unlike most leucine zipper proteins, cannot bind DNA. Upon induction by IFN-α, IFI-35 associates with Nmi (N-Myc-interacting protein), resulting in the formation of a high molecular weight complex that is thought to play a role in IFN-α signaling and cellular responses. Once complexed with Nmi, IFI-35 is unable to be degraded by the proteasome, suggesting that IFI-35 is protected from degradation only when needed by IFN-α. Two isoforms of IFI-35 exist due to alternative splicing events.

    UniProt

    P80217
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