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IFI35 抗体

IFI35 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7259096
发货至: 中国
  • 抗原 See all IFI35 抗体
    IFI35 (Interferon-Induced Protein 35 (IFI35))
    适用
    • 39
    • 6
    • 6
    • 4
    • 4
    • 4
    人, 小鼠
    宿主
    • 34
    • 5
    克隆类型
    • 37
    • 2
    多克隆
    标记
    • 17
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IFI35 antibody is un-conjugated
    应用范围
    • 31
    • 16
    • 16
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    产品特性
    Polyclonal Antibody
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein of human IFI35 (NP_005524.2).
    亚型
    IgG
    Top Product
    Discover our top product IFI35 Primary Antibody
  • 应用备注
    WB 1:500-1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    IFI35 (Interferon-Induced Protein 35 (IFI35))
    别名
    IFI35 (IFI35 产品)
    别名
    IFI35 antibody, IFP35 antibody, 2010008K16Rik antibody, AW986054 antibody, ifi-35 antibody, interferon induced protein 35 antibody, interferon-induced protein 35 antibody, IFI35 antibody, ifi35 antibody, Ifi35 antibody
    背景
    The Interferon family of proteins are able to alter the expression of a variety of target genes, thereby controlling various events within the cell. IFI-35 (Interferon-induced 35 kDa protein), also known as IFP35, is a 286 amino acid interferon-induced protein. Localized to the nucleus and expressed in macrophages, fibroblasts and epithelial cells, IFI-35 is a leucine zipper protein that can form homodimers, but, unlike most leucine zipper proteins, cannot bind DNA. Upon induction by IFN-α, IFI-35 associates with Nmi (N-Myc-interacting protein), resulting in the formation of a high molecular weight complex that is thought to play a role in IFN-α signaling and cellular responses. Once complexed with Nmi, IFI-35 is unable to be degraded by the proteasome, suggesting that IFI-35 is protected from degradation only when needed by IFN-α. Two isoforms of IFI-35 exist due to alternative splicing events.
    分子量

    Observed_MW: 35 kDa

    Calculated_MW: 31 kDa

    基因ID
    3430
    UniProt
    P80217
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