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GFI1 抗体

This anti-GFI1 antibody is a 兔 多克隆 antibody detecting GFI1 in ELISA 和 IHC. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN7245050
发货至: 中国

Quick Overview for GFI1 抗体 (ABIN7245050)

抗原

See all GFI1 抗体
GFI1 (Growth Factor Independent 1 (GFI1))

适用

  • 23
  • 16
  • 15
  • 5
  • 4
  • 4
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
人, 大鼠, 小鼠

宿主

  • 17
  • 7

克隆类型

  • 19
  • 5
多克隆

标记

  • 17
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This GFI1 antibody is un-conjugated

应用范围

  • 16
  • 8
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
ELISA, Immunohistochemistry (IHC)
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Antigen affinity purification

    免疫原

    Synthetic peptide of human GFI1

    亚型

    IgG
  • 应用备注

    IHC 1:50-1:300, ELISA 1:5000-1:10000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.62 mg/mL

    缓冲液

    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    GFI1 (Growth Factor Independent 1 (GFI1))

    别名

    GFI1

    背景

    This gene encodes a nuclear zinc finger protein that functions as a transcriptional repressor. This protein plays a role in diverse developmental contexts, including hematopoiesis and oncogenesis. It functions as part of a complex along with other cofactors to control histone modifications that lead to silencing of the target gene promoters. Mutations in this gene cause autosomal dominant severe congenital neutropenia, and also dominant nonimmune chronic idiopathic neutropenia of adults, which are heterogeneous hematopoietic disorders that cause predispositions to leukemias and infections. Multiple alternatively spliced variants, encoding the same protein, have been identified for this gene.

    UniProt

    Q99684
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