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CDC123 抗体

This anti-CDC123 antibody is a 兔 多克隆 antibody detecting CDC123 in WB 和 ELISA. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN7244567
发货至: 中国

Quick Overview for CDC123 抗体 (ABIN7244567)

抗原

See all CDC123 抗体
CDC123 (Cell Division Cycle 123 Homolog (CDC123))

适用

  • 51
  • 9
  • 4
  • 1
  • 1
人, 大鼠, 小鼠

宿主

  • 43
  • 8

克隆类型

  • 44
  • 7
多克隆

标记

  • 21
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CDC123 antibody is un-conjugated

应用范围

  • 24
  • 17
  • 16
  • 13
  • 13
  • 9
  • 9
  • 5
  • 5
  • 4
  • 3
Western Blotting (WB), ELISA
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Antigen affinity purification

    免疫原

    Synthetic peptide of human CDC123

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, ELISA 1:5000-1:10000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.9 mg/mL

    缓冲液

    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    CDC123 (Cell Division Cycle 123 Homolog (CDC123))

    别名

    CDC123

    背景

    The eukaryotic cell division cycle consists of a number of gene-controlled sequences that involve cyclin dependent kinases (Cdks) and cell division control (Cdc) proteins. Cdc123 (Cell division cycle protein 123), also known as D123, is a 336 amino acid cytoplasmic protein that is involved in cell cycle control. Widely expressed with high expression in thymus, spleen, ovary, testis, small intestine and leukocytes, Cdc123 functions to destabilize Chfr (checkpoint with forkhead and ring finger domain) proteins which, when accumulated, block the G to S phase transition. Cdc123 prevents the Chfr proteins from collecting in the cell, thereby allowing the cell to enter the S phase. Due to its role in cell cycle control, Cdc123 is thought to be a basal marker for luminal breast cancers.

    分子量

    Observed_MW: Refer to figures

    Calculated_MW: 39 kDa

    UniProt

    O75794
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