TTI1 抗体
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北京 101111
Quick Overview for TTI1 抗体 (ABIN7244333)
抗原
See all TTI1 抗体适用
宿主
克隆类型
标记
应用范围
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产品特性
- Polyclonal Antibody
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纯化方法
- Affinity purification
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免疫原
- Synthetic peptide of human TTI1
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亚型
- IgG
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应用备注
- IHC 1:30-150, ELISA 1:2000-10000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.2 mg/mL
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缓冲液
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- TTI1 (TELO2 Interacting Protein 1 (TTI1))
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别名
- TTI1
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背景
- Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals.
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NCBI登录号
- NP_055472
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UniProt
- O43156
抗原
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