RNF43 抗体
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北京 101111
Quick Overview for RNF43 抗体 (ABIN7003084)
抗原
See all RNF43 抗体适用
宿主
克隆类型
标记
应用范围
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产品特性
- Polyclonal Antibody
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纯化方法
- Affinity purification
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免疫原
- Synthetic peptide of human RNF43
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亚型
- IgG
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应用备注
- WB 1:200-1:1000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.7 mg/mL
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缓冲液
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- RNF43 (Ring Finger Protein 43 (RNF43))
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别名
- RNF43
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背景
- RNF43 (ring finger protein 43), also known as URCC or RNF124, is a 783 amino acid single-pass type I membrane protein of the Endoplasmic reticulum and nuclear envelope that is thought to function as an E3 ubiquitin-protein ligase. Containing one RING-type zinc finger and existing as four alternatively spliced isoforms, RNF43 is expressed in fetal kidney and lung, as well as in cancers of the lung, colon and kidney. RNF43 functions as a cytotoxic T lymphocyte tumor antigen, and is therefore considered a target for cancer immunotherapy.
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分子量
- 86 kDa
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NCBI登录号
- NP_060233
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UniProt
- Q68DV7
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途径
- WNT signaling
抗原
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