ERN2 抗体
This anti-ERN2 antibody is a 兔 多克隆 antibody detecting ERN2 in ELISA 和 IHC. Suitable for 人.
Quick Overview for ERN2 抗体 (ABIN7238930)
抗原
See all ERN2 抗体
ERN2
(Endoplasmic Reticulum To Nucleus Signaling 2 (ERN2))
适用
人
宿主
兔
克隆类型
多克隆
标记
This ERN2 antibody is un-conjugated
应用范围
ELISA, Immunohistochemistry (IHC)
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产品特性
- Polyclonal Antibody
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纯化方法
- Affinity purification
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免疫原
- Synthetic peptide of human ERN2
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亚型
- IgG
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anti-Endoplasmic Reticulum To Nucleus Signaling 2 (ERN2) (AA 841-890) antibody
ERN2 适用: 人, 小鼠 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- IHC 1:50-1:200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- ERN2 (Endoplasmic Reticulum To Nucleus Signaling 2 (ERN2))
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别名
- ERN2
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背景
- The accumulation of unfolded proteins within the endoplasmic recticulum (ER) of yeast and mammalian cells activates the unfolded protein response (UPR) pathway and leads to the transcription of ER-specific genes involved in protein folding. The activation of the UPR requires the ER transmembrane kinase IRE1p (for inositol-requiring and ER-to-nucleus signaling protein). IRE1α and IRE1β are two mammalian homologs of the yeast IRE1p. These related proteins localize to the ER lumen and contain both a short transmembrane domain that spans the ER membrane and a cytosolic Ser/Thr kinase domain. IRE1 activation involves the oligomerization and trans-phosphorylation of the cytosolic portion of the proteins, which then potentiates its intrinsic kinase activity and, in turn, stimulates transcription of UPR-targeted genes.
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NCBI登录号
- NP_150296
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UniProt
- Q76MJ5
抗原
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