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FZD6 抗体

This anti-FZD6 antibody (ABIN7238471) is a Rabbit Polyclonal antibody detecting FZD6 in ELISA, IHC. Suitable for Human, Mouse.
产品编号 ABIN7238471
发货至: 中国

Quick Overview for FZD6 抗体 (ABIN7238471)

抗原

See all FZD6 抗体
FZD6 (Frizzled Family Receptor 6 (FZD6))

适用

  • 37
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人, 小鼠

宿主

  • 36
  • 2
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克隆类型

  • 39
  • 3
多克隆

标记

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This FZD6 antibody is un-conjugated

应用范围

  • 28
  • 15
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  • 1
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ELISA, Immunohistochemistry (IHC)
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Affinity purification

    免疫原

    Synthetic peptide of human FZD6

    亚型

    IgG
  • 应用备注

    IHC 1:100-1:300

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    FZD6 (Frizzled Family Receptor 6 (FZD6))

    别名

    FZD6

    背景

    This gene represents a member of the 'frizzled' gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif. This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting the processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis. Alternative splicing results in multiple transcript variants, some of which do not encode a protein with a predicted signal peptide.

    NCBI登录号

    NP_001158087

    UniProt

    O60353

    途径

    WNT signaling, Tube Formation
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