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Desmoplakin 抗体

This anti-Desmoplakin antibody is a 兔 多克隆 antibody detecting Desmoplakin in IHC 和 ELISA. Suitable for 人 和 小鼠.
产品编号 ABIN7237973
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Desmoplakin 抗体 (ABIN7237973)

抗原

See all Desmoplakin (DSP) 抗体
Desmoplakin (DSP)

适用

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人, 小鼠

宿主

  • 39
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克隆类型

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多克隆

标记

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This Desmoplakin antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), ELISA
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Affinity purification

    免疫原

    Synthetic peptide of human DSP

    亚型

    IgG
  • 应用备注

    IHC 1:50-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    Desmoplakin (DSP)

    别名

    DSP

    背景

    Desmosomes are intercellular junctions that tightly link adjacent cells. Desmoplakin is an obligate component of functional desmosomes that anchors intermediate filaments to desmosomal plaques. The N-terminus of desmoplakin is required for localization to the desmosome and interacts with the N-terminal region of plakophilin 1 and plakoglobin. The C-terminus of desmoplakin binds with intermediate filaments. In the mid-region of desmoplakin, a coiled-coiled rod domain is responsible for homodimerization. Mutations in this gene are the cause of several cardiomyopathies and keratodermas as well as the autoimmune disease paraneoplastic pemphigus.

    NCBI登录号

    NP_004406

    UniProt

    P15924

    途径

    Cell-Cell Junction Organization
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