Desmoplakin 抗体
Quick Overview for Desmoplakin 抗体 (ABIN7237973)
抗原
See all Desmoplakin (DSP) 抗体适用
宿主
克隆类型
标记
应用范围
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产品特性
- Polyclonal Antibody
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纯化方法
- Affinity purification
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免疫原
- Synthetic peptide of human DSP
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亚型
- IgG
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anti-Desmoplakin (DSP) (AA 2609-2822) antibody
DSP 适用: 人 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Desmoplakin (DSP) antibodyDSP 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Desmoplakin (DSP) antibodyDSP 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Desmoplakin (DSP) (AA 1-100) antibodyDSP 适用: 人 IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-Desmoplakin (DSP) (Internal Region) antibodyVerified DSP 适用: 人 IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Desmoplakin (DSP) (C-Term) antibodyDSP 适用: 人, 小鼠 IHC, ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Desmoplakin (DSP) (AA 2750-2850) antibodyDSP 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- IHC 1:50-1:200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- Desmoplakin (DSP)
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别名
- DSP
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背景
- Desmosomes are intercellular junctions that tightly link adjacent cells. Desmoplakin is an obligate component of functional desmosomes that anchors intermediate filaments to desmosomal plaques. The N-terminus of desmoplakin is required for localization to the desmosome and interacts with the N-terminal region of plakophilin 1 and plakoglobin. The C-terminus of desmoplakin binds with intermediate filaments. In the mid-region of desmoplakin, a coiled-coiled rod domain is responsible for homodimerization. Mutations in this gene are the cause of several cardiomyopathies and keratodermas as well as the autoimmune disease paraneoplastic pemphigus.
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NCBI登录号
- NP_004406
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UniProt
- P15924
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途径
- Cell-Cell Junction Organization
抗原
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