RGS1 抗体
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北京 101111
Quick Overview for RGS1 抗体 (ABIN7237642)
抗原
See all RGS1 抗体适用
宿主
克隆类型
标记
应用范围
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产品特性
- Polyclonal Antibody
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纯化方法
- Affinity purification
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免疫原
- Recombinant protein of human RGS1
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亚型
- IgG
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应用备注
- WB 1:500-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.3 mg/mL
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缓冲液
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- RGS1 (Regulator of G-Protein Signaling 1 (RGS1))
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别名
- RGS1
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背景
- This gene encodes a member of the regulator of G-protein signalling family. This protein is located on the cytosolic side of the plasma membrane and contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signalling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.
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分子量
- 24 kDa
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UniProt
- Q08116
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途径
- MAPK Pathway, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events
抗原
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