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DOK4 抗体

This anti-DOK4 antibody is a 兔 多克隆 antibody detecting DOK4 in IHC 和 ELISA. Suitable for 人 和 小鼠.
产品编号 ABIN7236107
发货至: 中国

Quick Overview for DOK4 抗体 (ABIN7236107)

抗原

See all DOK4 抗体
DOK4 (Docking Protein 4 (DOK4))

适用

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人, 小鼠

宿主

  • 49

克隆类型

  • 49
多克隆

标记

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This DOK4 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), ELISA
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Affinity purification

    免疫原

    Recombinant protein of human DOK4

    亚型

    IgG
  • 应用备注

    IHC 1:50-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    DOK4 (Docking Protein 4 (DOK4))

    别名

    DOK4

    背景

    Docking protein 4is aproteinthat in humans is encoded by theDOK4gene. Dok-4 is a 326 amino acid protein that contains one PH domain and one IRS-type PTB domain and belongs to the Dok family of interacting proteins. Expressed in a variety of tissues with highest expression in liver, heart, kidney and skeletal muscle, Dok-4 plays an important role in Ret-mediated neurite outgrowth and may link Ret with downstream effectors during neuronal differentiation. Additionally, Dok-4 is thought to play a positive role in the activation of MAPK pathways and may participate in T-cell induced immune system regulation. Overexpression of Dok-4 is associated with clear cell renal cell carcinoma, suggesting a role for Dok-4 in tumorigenesis.

    UniProt

    Q8TEW6
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