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Tropomyosin 抗体

This anti-Tropomyosin antibody is a 兔 多克隆 antibody detecting Tropomyosin in WB, ELISA 和 IHC. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN7235637
发货至: 中国

Quick Overview for Tropomyosin 抗体 (ABIN7235637)

抗原

See all Tropomyosin (TPM1) 抗体
Tropomyosin (TPM1) (Tropomyosin 1 (Alpha) (TPM1))

适用

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人, 大鼠, 小鼠

宿主

  • 44
  • 12

克隆类型

  • 34
  • 22
多克隆

标记

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This Tropomyosin antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Affinity purification

    免疫原

    Recombinant protein of human TPM1

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, IHC 1:50-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.1 mg/mL

    缓冲液

    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    Tropomyosin (TPM1) (Tropomyosin 1 (Alpha) (TPM1))

    别名

    TPM1

    背景

    This gene is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The encoded protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction. In smooth muscle and non-muscle cells, alternatively spliced transcript variants encoding a range of isoforms have been described. Mutations in this gene are associated with type 3 familial hypertrophic cardiomyopathy.

    分子量

    33 kDa

    UniProt

    P09493

    途径

    Regulation of Actin Filament Polymerization
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