Cathepsin B 抗体
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- 抗原 See all Cathepsin B (CTSB) 抗体
- Cathepsin B (CTSB)
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Cathepsin B antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), ELISA
- 产品特性
- Polyclonal Antibody
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant protein of human CTSB
- 亚型
- IgG
- Top Product
- Discover our top product CTSB Primary Antibody
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- 应用备注
- IHC 1:150-1:500
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.8 mg/mL
- 缓冲液
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- Cathepsin B (CTSB)
- 别名
- Cathepsin B (CTSB 产品)
- 背景
- The protein encoded by this gene is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer disease, the most common cause of dementia. Overexpression of the encoded protein, which is a member of the peptidase C1 family, has been associated with esophageal adenocarcinoma and other tumors. At least five transcript variants encoding the same protein have been found for this gene.
- UniProt
- P07858
- 途径
- Activation of Innate immune Response, Toll-Like Receptors Cascades
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