MCAM 抗体
Quick Overview for MCAM 抗体 (ABIN6999958)
抗原
See all MCAM 抗体适用
宿主
克隆类型
标记
应用范围
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产品特性
- Polyclonal Antibody
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纯化方法
- Antigen Affinity Purification
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免疫原
- Recombinant Human Cell surface glycoprotein MUC18 protein
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亚型
- IgG
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应用备注
- WB 1:500-1:1000 IHC 1:50-1:100
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.48 mg/mL
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缓冲液
- PBS with 0.05 % Proclin300, 50 % glycerol, pH 7.3
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- MCAM (Melanoma Cell Adhesion Molecule (MCAM))
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别名
- CD146
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背景
- CD146,also known as melanoma cell adhesion molecule (MCAM) or MUC18,originally identified as a biomarker of melanoma progression,is a transmembrane glycoprotein belonging to the immunoglobulin (Ig) superfamily . Structurally,it consists of five Ig domains,a transmembrane domain,and a cytoplasmic region. In normal adult tissue,CD146 is primarily expressed by vascular endothelium and smooth muscle. CD146 is a key cell adhesion protein in vascular endothelial cell activity and angiogenesis,and has been used as marker of circulating endothelium cells (CECs) .
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分子量
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Observed_MW: 57,71 kDa
Calculated_MW: 57,71 kDa
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基因ID
- 4162
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UniProt
- P43121
抗原
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