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RIPK3 抗体 (C-Term)

RIPK3 适用: 人 WB, ELISA, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6992283
发货至: 中国
  • 抗原 See all RIPK3 抗体
    RIPK3 (Receptor-Interacting serine-threonine Kinase 3 (RIPK3))
    抗原表位
    • 10
    • 8
    • 8
    • 8
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    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 78
    • 41
    • 19
    • 6
    • 4
    • 4
    • 2
    • 1
    宿主
    • 79
    • 9
    克隆类型
    • 79
    • 9
    多克隆
    标记
    • 43
    • 9
    • 8
    • 7
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    This RIPK3 antibody is un-conjugated
    应用范围
    • 81
    • 51
    • 43
    • 17
    • 11
    • 8
    • 5
    • 4
    • 4
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    特异性
    Several isoforms of hRIP3 are known to exist.
    纯化方法
    hRIP3 Antibody is affinity chromatography purified via peptide column.
    免疫原
    Anti-hRIP3 antibody was raised against a peptide corresponding to 18 amino acids near the carboxy terminus of human hRIP3. The immunogen is located within the last 50 amino acids of hRIP3.
    亚型
    IgG
    Top Product
    Discover our top product RIPK3 Primary Antibody
  • 应用备注
    WB: 0.5-1 μ,g/mL, IF: 20 μ,g/mL, IHC: 2-5 μ,g/mL.

    Antibody validated: Western Blot, Immunofluorescence and Immunohistochemistry in human samples. All other applications and species not yet tested.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    hRIP3 Antibody is supplied in PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,4 °C
    储存方法
    hRIP3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    RIPK3 (Receptor-Interacting serine-threonine Kinase 3 (RIPK3))
    别名
    hRIP3 (RIPK3 产品)
    别名
    RIPK3 antibody, RIP3 antibody, 2610528K09Rik antibody, AW107945 antibody, Rip3 antibody, Hcyp2 antibody, receptor interacting serine/threonine kinase 3 antibody, receptor interacting serine/threonine kinase 3 S homeolog antibody, receptor-interacting serine-threonine kinase 3 antibody, RIPK3 antibody, ripk3.S antibody, Ripk3 antibody
    背景
    HRIP3 Antibody: Certain serine/threonine protein kinases, such as ASK1, RIP, DAP, and ZIP kinases, are mediators of apoptosis. Receptor interacting proteins including RIP and RIP2/RICK mediate apoptosis induced by TNFR1 and Fas, two prototype members in the death receptor family. A novel member in the RIP kinase family was recently identified and designated RIP3. RIP3 contains N-terminal kinase domain but, unlike RIP or RIP2, lacks the C-terminal death or CARD domain. RIP3 binds to RIP and TNFR1, mediates TNFR1 induced apoptosis, and attenuates RIP and TNFR1 induced NF-?B activation. Overexpression of RIP3 induces apoptosis and NF-?B activation. The messenger RNA of RIP3 is expressed in a subset of adult tissues.
    分子量
    Predicted: 57kD

    Observed: 57 kD kDa
    基因ID
    11035
    UniProt
    Q9Y572
    途径
    Activation of Innate immune Response, Toll-Like Receptors Cascades
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