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CD276 抗体 (C-Term)

CD276 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6992208
发货至: 中国
  • 抗原 See all CD276 抗体
    CD276
    抗原表位
    • 15
    • 6
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 484-534, C-Term
    适用
    • 56
    • 33
    • 9
    • 6
    • 6
    • 3
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 41
    • 16
    • 6
    • 1
    克隆类型
    • 37
    • 26
    • 1
    多克隆
    标记
    • 36
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD276 antibody is un-conjugated
    应用范围
    • 48
    • 22
    • 20
    • 14
    • 13
    • 9
    • 8
    • 8
    • 7
    • 3
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    特异性
    At least three antibodies are known to exist, this antibody will detect all three isoforms.
    纯化方法
    CD276 Antibody is affinity chromatography purified via peptide column.
    免疫原
    CD276 antibody was raised against a peptide corresponding to 19 amino acids near the carboxy terminus of CD276. The immunogen is located within amino acids 484 - 534 of CD276.
    亚型
    IgG
    Top Product
    Discover our top product CD276 Primary Antibody
  • 应用备注
    CD276 antibody can be used for Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for Immunohistochemistry at 2 μ,g/mL. For Immunoflorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human and mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    CD276 Antibody is supplied in PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,4 °C
    储存方法
    CD276 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    CD276
    别名
    CD276 (CD276 产品)
    别名
    sc:d0645 antibody, zgc:158279 antibody, 6030411F23Rik antibody, AU016588 antibody, B7RP-2 antibody, B7h3 antibody, B7H3 antibody, 4Ig-B7-H3 antibody, B7-H3 antibody, CD276 molecule antibody, CD276 molecule S homeolog antibody, CD276 antigen antibody, Cd276 molecule antibody, CD276 antibody, cd276.S antibody, cd276 antibody, Cd276 antibody
    背景
    CD276, also known as B7-H3, was initially identified as a member of the B7 family of proteins through its homology with previously identified B7 Molecules (1). CD276 mRNA is widely expressed, but its protein expression is usually rather low (2). CD276 has been shown to play a role in both the costimulation as well as the coinhibition of T cell response (3). In a similar fashion, CD276 plays a critical role in the control of antitumor immune responses in some cases, while in others appears to mediate antitumor immunity (4). It thus joins other immune checkpoint proteins as a possible therapeutic target for at least a subset of cancers.
    分子量
    Predicted: 35, 43, 57 kDa

    Observed: 59 kDa
    基因ID
    80381
    NCBI登录号
    NP_001019907
    UniProt
    Q5ZPR3
    途径
    Cancer Immune Checkpoints
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