CD276 抗体 (C-Term)
Quick Overview for CD276 抗体 (C-Term) (ABIN6992208)
抗原
See all CD276 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 484-534, C-Term
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特异性
- At least three antibodies are known to exist, this antibody will detect all three isoforms.
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纯化方法
- CD276 Antibody is affinity chromatography purified via peptide column.
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免疫原
- CD276 antibody was raised against a peptide corresponding to 19 amino acids near the carboxy terminus of CD276. The immunogen is located within amino acids 484 - 534 of CD276.
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亚型
- IgG
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anti-CD276 (CD276) (AA 47-219) antibody
CD276 适用: 人 WB, FACS, IHC 宿主: 兔 Polyclonal unconjugated
anti-CD276 (CD276) (AA 29-466) antibodyCD276 适用: 人 ELISA, FACS, IHC, ICC 宿主: 小鼠 Monoclonal 8C1C2 unconjugated
anti-CD276 (CD276) (AA 47-213) antibodyCD276 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD276 (CD276) antibodyCD276 适用: 人 ELISA, FACS, IHC 宿主: 小鼠 Monoclonal 6A1 unconjugated
anti-CD276 (CD276) (AA 493-522), (C-Term) antibodyCD276 适用: 人 WB, FACS, IHC (p), IF 宿主: 兔 Polyclonal RB31111 unconjugated
anti-CD276 (CD276) (AA 237-358) antibodyCD276 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4E12 unconjugated
anti-CD276 (CD276) (AA 100-200) antibodyCD276 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-CD276 (CD276) (AA 101-200) antibodyCD276 适用: 人, 小鼠 WB, ELISA, IHC (p), ICC, IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-CD276 (CD276) (AA 47-219) antibodyCD276 适用: 人 WB 宿主: 小鼠 Monoclonal C9 unconjugated
anti-CD276 (CD276) (AA 29-200) antibodyCD276 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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CD276 antibody can be used for Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for Immunohistochemistry at 2 μ,g/mL. For Immunoflorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human and mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- CD276 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- CD276 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- CD276
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别名
- CD276
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背景
- CD276, also known as B7-H3, was initially identified as a member of the B7 family of proteins through its homology with previously identified B7 Molecules (1). CD276 mRNA is widely expressed, but its protein expression is usually rather low (2). CD276 has been shown to play a role in both the costimulation as well as the coinhibition of T cell response (3). In a similar fashion, CD276 plays a critical role in the control of antitumor immune responses in some cases, while in others appears to mediate antitumor immunity (4). It thus joins other immune checkpoint proteins as a possible therapeutic target for at least a subset of cancers.
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分子量
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Predicted: 35, 43, 57 kDa
Observed: 59 kDa -
基因ID
- 80381
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NCBI登录号
- NP_001019907
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UniProt
- Q5ZPR3
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途径
- Cancer Immune Checkpoints
抗原
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