SRPK1 抗体 (N-Term)
Our Local Distributor
北京 101111
Quick Overview for SRPK1 抗体 (N-Term) (ABIN6992178)
抗原
See all SRPK1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- N-Term
-
特异性
- SRPK1 antibody is human, mouse and rat reactive. Multiple isoforms of SRPK1 are known to exist, this antibody will detect all except isoforms b and e. SRPK1 antibody is predicted to not cross-react with SRPK2.
-
纯化方法
- SRPK1 Antibody is affinity chromatography purified via peptide column.
-
免疫原
- SRPK1 antibody was raised against a 19 amino acid peptide from near the amino terminus of human SRPK1. The immunogen is located within the first 50 amino acids of SRPK1.
-
亚型
- IgG
-
-
-
-
应用备注
-
SRPK1 antibody can be used for the detection of SRPK1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry at 5 μ,g/mL.
Antibody validated: Western Blot in mouse samples and Immunohistochemistry in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- SRPK1 Antibody is supplied in PBS containing 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,4 °C
-
储存方法
- SRPK1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
-
-
- SRPK1 (SRSF Protein Kinase 1 (SRPK1))
-
别名
- SRPK1
-
背景
- SRPK1 and SRPK2, two Arginine/serine-rich (SR) protein-specific kinases constitute control circuits to regulate both constitutive and alternative pre-mRNA splicing and coordinate splicing with transcription in cells (1). They are highly specific for the phosphorylation of these RS proteins, and highly expressed in testis (1,2). SRPK1 plays a role in the condensation of sperm chromatin and controls the intranuclear distribution of splicing factors in interphase cells and the reorganization of nuclear speckles during mitosis (3,4).
-
分子量
-
Predicted: 54, 72, 91 kDa
Observed: 91 kDa -
基因ID
- 6732
-
NCBI登录号
- NP_003128
-
UniProt
- Q96SB4
-
途径
- Toll-Like Receptors Cascades
抗原
-